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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
21.82
Human Site:
S458
Identified Species:
43.64
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
S458
S
V
L
D
L
K
P
S
E
P
V
G
T
G
N
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
S459
S
V
L
D
L
K
P
S
E
P
V
G
T
G
N
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
S442
S
V
L
D
L
K
P
S
E
P
V
G
T
G
N
Dog
Lupus familis
XP_538964
685
76968
S511
S
V
L
D
L
K
P
S
E
P
V
G
T
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
S455
S
V
L
D
L
K
P
S
E
S
V
G
T
G
T
Rat
Rattus norvegicus
Q62726
629
70550
S455
S
V
L
D
L
K
P
S
E
P
V
G
T
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
G452
A
S
C
N
Q
A
R
G
E
N
K
S
L
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
R126
H
S
H
R
V
L
H
R
D
L
K
P
Q
N
L
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
L458
S
S
A
R
Q
H
Y
L
R
Q
S
R
Y
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
R398
E
R
V
Y
K
E
N
R
A
N
W
N
V
N
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
G405
L
E
G
S
R
G
F
G
G
T
S
A
K
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
L271
A
I
D
L
I
N
R
L
C
S
W
D
P
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
N.A.
0
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
20
N.A.
13.3
6.6
N.A.
N.A.
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
9
0
0
9
0
0
9
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
9
50
0
0
0
0
9
0
0
9
0
0
0
% D
% Glu:
9
9
0
0
0
9
0
0
59
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
17
9
0
0
50
0
50
0
% G
% His:
9
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
50
0
0
0
0
17
0
9
0
17
% K
% Leu:
9
0
50
9
50
9
0
17
0
9
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
0
9
9
0
0
17
0
9
0
17
34
% N
% Pro:
0
0
0
0
0
0
50
0
0
42
0
9
9
9
9
% P
% Gln:
0
0
0
0
17
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
9
0
17
9
0
17
17
9
0
0
9
0
0
0
% R
% Ser:
59
25
0
9
0
0
0
50
0
17
17
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
50
9
17
% T
% Val:
0
50
9
0
9
0
0
0
0
0
50
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _